References - Recreation and Sports

Get a Grip!

Gripping the golf club properly is the first step toward making a good golf swing. If you are not gripping the club in the correct ma

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

nner your swing could be affected in many different ways. The three keys to gripping a golf club correctly are fit, alignment, and pressure.

Fit – Ye

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ah Guys, Size Does Matter!

Grip size is probably the most important part of being able to grip the golf club properly. Too small of a grip can cause

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

the club to twist in your hands, a result of unconsciously squeezing the club at the bottom of the swing, resulting in a closed clubface. Too large of a

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

grip and the club may come loose at impact, opening the club face. Either way, you’re not going to be making good, solid contact with any amount of cons

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

istency.

Along with making sure the grip size is correct for your hands, you’ll need to make sure you are not playing with worn out grips. Grips become

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

worn out and slick through normal wear and tear, oxidization, and moisture damage. A tired or worn out grip will not provide the traction you need to kee

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

p the golf club stable throughout your swing. Replacing grips is easy and inexpensive and can make a world of difference in your golf game.

Alignment

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

– Pointing the V’s!

Having the proper grip alignment is a key factor in getting the clubface squared at impact. Too weak of a grip, rotating one or

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

both hands away from the other, promotes an open clubface, resulting in a push or slice. Too strong of a grip, rotating one or both hands more towards t

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

he other, promotes a closed clubface, resulting in a pull or hook.

The best way to make sure that your grip is properly aligned is to check the V’s. The

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

V’s are the angle between your thumb and forefinger on each hand. These should point between your chin and back shoulder.

Experiment with weaker and st

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ronger grips at the driving range to see how they affect your ball flight. You’ll find that the only way to consistently make accurate golf shots is by k

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

eeping your grip aligned properly.

Pressure - Firm and Relaxed – Don’t Choke It!

The most common mistake golfers make is trying to choke the golf

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

club. They figure that if you squeeze harder you’ll hit the ball harder. Wrong! Choking the golf club actually tenses the muscles in your arms, which

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

hinders a smooth swing and follow through, resulting in less distance and accuracy.

You want to be able to grip the club firmly, while keeping your arms

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

relaxed. Only put enough pressure on it to keep it from sliding around in your hands. If you are not applying enough pressure the golf club will twist a

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

nd rotate during the swing. To make sure you’ve got it right, have someone try and pull the golf club out of your grip. They shouldn’t be able to. If t

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

hey can, tighten your grip a little bit. Just make sure to keep your arms relaxed.

Remember, having the proper grip will lay the foundation for a good g

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

olf swing. Don't change your grip to correct a problem somewhere else or you could end up with an even less consistent golf swing and poorer shot results

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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References - Gripping the Golf Club Properly Lays the Foundation for a Good Golf Swing

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