References - Recreation and Sports

Do you like to run but find excuses not to? Is it too hot? Too cold? Too wet? Too much hassle to get out? We al

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

l have our favourite excuses for not getting out, don't we? So how do you stay motivated?

Keep a training l

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

g A running log can allow you to plot your routes and record your training runs. You'll be impressed when

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

you see your times and weight come down and your speed and fitness go up. Tracking your progress over several w

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

eks and months is great motivation. There is nothing like breaking your personal bests! Once you build up a his

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

tory of training times you'll be able to see how you perform on different sectors. Again you'll be uplifted by

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

improving on a sector record. You can also identify which sectors are your slowest. Work to improve them and s

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ee that improvement reflected over time in your running diary.

Enter a race There is nothing like signi

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

g up for a race to get you out training. Set yourself a target of racing 2, 3 or even 6 months down the line an

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

d work towards that race. Intersperse your training with other races to break up the routine of training. If yo

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

are aiming to run a half marathon, schedule a 10k. If you've never been in a race before try one of the big ci

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

y events where you'll be wowed by the whole experience.

Use different routes Don't choose the same old

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

route and distance time after time. Run different distances on different terrain. Vary the scenery that you see

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

Be inspired by running near a river, through woods or past magnificent buildings. Enter races in places you've

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

never visited but have always wished to see – make a weekend of it!

Cross train Build in other exercis

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

s to ease any strain on your body or mind. Listen to your body. If you feel tired or achy try something differe

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

nt. Swimming is excellent exercise as there is no impact on your muscles or joints. Even walking a few miles a

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

a brisk pace can be effective as part of your training program.

Run with friends If you run with a fri

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

end or group of friends you'll feel guilty about letting them down. You won't want to wimp out! You'll also hav

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

the benefit, of course, of being able to chat with your training partner as you run.

Above all enjoy yourself

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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