References - Recreation and Sports

Bristol City

Odds: 6/1

Last Five Seasons
2005/06 - 9 (League One), 2004/05 - 7 (League One), 2003/04 - 3 (League One), 2002/03 - 3

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

(League One), 2001/02 - 7 (League One).

2005/06 Cup Progress
FA Cup First Round vs Notts County (h) - lost 2-1.
Carling Cup Fir

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

t Round vs Barnet (h) - lost 4-2.
Football League Trophy Southern Section First Round vs Barnet (a) - lost 3-2.

Top Goal Scorer 2005

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

/06: Steve Brooker (striker) - 16 goals.

Players In
Phil Jevons (Yeovil Town - Free), Jamie McCombe (Lincoln City - Free), Liam Font

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ine (Fulham - Free), Enoch Showunmi (Luton Town - Free), Chris Weale (Yeovil Town - Free).

Players Out
Luke Wilkshire (FC Twente - F

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ree), Steve Phillips (Bristol Rovers - Free).

After a dire start to last season which saw them exit all Cup competitions at the first hur

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

le, lose 7-1 at Swansea City and go on a seven match losing streak between October and December, Bristol City ended last season well and f

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

inished in ninth position.

This season, manager Gary Johnson wants to build on the solid form shown in the second half of last term and h

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

s set his side a target of 90 points. This figure should see the club claim automatic promotion to the Championship following several year

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

s in and around the play offs. The bookmakers make City second favourites to win the division outright behind Nottingham Forest.

Johnson

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

as signed striker Phil Jevons who netted 45 goals in his two seasons at Yeovil Town and sees him as the ideal foil for last season’s top g

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

al scorer Steve Brooker. Brooker himself has signed a one year contract extension and is tied to the club until the end of the 2008/09 cam

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

paign, ending speculation he was a target of Championship outfit Norwich City

Goalkeeper Chris Weale is the second arrival from Johnson’s

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

former club Yeovil Town and after signing an initial one year deal, this will extend to two years once he has played 10 games next season.

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

Other new faces arriving this summer ate Fulham defender Liam Fontaine, who had a loan spell at the club last season and Luton Town strik

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

r Enoch Showumni. Both players have agreed two year contracts at Ashton Gate. Showumni has started 40 league games for Championship side L

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

uton Town and has scored 14 goals.

One player on his way out is Australian international Luke Wilkshire who represented his country in th

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

s summer’s World Cup. The 24 year old joined the Robins from Middlesbrough in 2003 for ?250,000 and made 103 appearances for City.

Verdic

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

t
If City can recreate the form that saw them win eight out of their last 12 matches last season then an automatic promotion spot is

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ithin their grasp. Johnson has plenty of fire power at his disposal but the Robins need to get off to a good start to avoid disappointment

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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References - League One Season Preview 2006/07 - Bristol City

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