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References - Metal Detectors - How They Work
Today there are metal detectors which are small enough to be hand held and you will often find them being used at securi
According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
ty points at airports and train stations across the world where they will be able to locate a metal object which has bee
; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.
Examples of combination products may in
Examples of combination products may in
n detected by a walk through system.
There are some which can be carried in order to scan for metal objects in the grou
There are some which can be carried in order to scan for metal objects in the grou
lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.
nd such as nails, loose change or landmines. Any such hand held metal detector operates very much on the same principals
here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
as a walk through metal detector as they emit time varying electromagnetic fields and will then listen for waves coming
d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.
Combination pro
Combination pro
back from conducting objects. There are even some models which will further analyze the returned waves to distinguish w
ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
hich common metal it is.
Certainly for sometime now hand held metal detectors have been used for searching for landmine
Certainly for sometime now hand held metal detectors have been used for searching for landmine
easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
s (unfortunately a many landmines are now largely made from plastic) and so with new technologies such as neutron activa
nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
tion and ground penetration systems which are being developed in order that searches can be carried out for such landmin
and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
es that are not made from metal.
Most hand held metal detectors work by use of an electromagnetic field which detects t
Most hand held metal detectors work by use of an electromagnetic field which detects t
ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
he presence of any metallic objects that are hidden. There are two ways in which metal detectors use electromagnetism ei
ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.
Following aspects would a
Following aspects would a
ther active or passive and below is a short description of each type.
1. Active - This method illuminates some detectio
1. Active - This method illuminates some detectio
dd to the challenges in developing combination products:
Which markets to tap where the combination products can do fairly well?
Which combination prod
Which markets to tap where the combination products can do fairly well?
Which combination prod
n space say an opening through which you have to walk (walk through metal detector) or in the space directly in front of
cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
you with the use of a hand held version. Energy which is reflected from or passes through the detection space is affect
tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
ed by the presence of any conductive material and the detector detects metal by measuring these effects.
2. Passive - T
2. Passive - T
t?
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
his method does not illuminate the detection space rather it takes advantage of the fact that every unshielded detection
ping new procedures for reviewing their safety, efficacy and quality.
Professional from academic institutions, pharmaceutical industries, health care indust
Professional from academic institutions, pharmaceutical industries, health care indust
space is being permeated by the Earth's natural magnetic field and any Ferromagnetic object (metals such as iron which
y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
are capable of being magnetized) that is moving through this detection space will cause a temporary but detectable chang
.
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
e in this natural field. Unfortunately, metal objects made from aluminum which is conducting but not Ferromagnetic can n
elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.
Companies that provide selfless information through particip
Companies that provide selfless information through particip
ot be detected by a passive metal detector.
Metal detectors continue to evolve over time and now you know how they work
Metal detectors continue to evolve over time and now you know how they work
tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products
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