References - Travel and Leisure

The Tengger caldera stretches out afar. With a diameter of 8 – 10km. the whole area covers not less than 5,250 hectares. But at this time of day what can be seen is only the sloping edges. A white mist seems to hang over it, covering most of the gaping

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

crater.

In the center, five peaks jut up from the haze, namely the mountains Bromo, Batok, Widodaren, Kursi and Giri. In the far background, is Mount Semeru (3,6976 meters above sea level), the highest peak on the whole island of Java, standing tall

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

acting as an anchor to all the natural splendor that meets the eye at this point. Meanwhile, volcanic smoke can be seen billowing continuously from Bromo, with occasional mushroom clouds puffing up from the symmetrical peak of Semeru, adding to the spe

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

tacular views. A larger that life sensation.

The red shades of the eastern horizon gradually yellow. Slowly but surely, the sun’s glory emerges from behind the obscure mountain ranges of the island’s east. The exceptional outlook becomes even clearer

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

as the solar rays sweep the peaks and pierce the mists… breathtaking.

This is the most famous and distinguished natural showcase of Bromo at its best. Hundreds of people come every year to be able to experience the emergence of the Tengger caldera at

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

unrise.

It is said that long ago lived a beautiful woman known by the name Roro Anteng. Because of her attractiveness, there came a day when an evil giant who possessed magical powers approached her to propose. Not daring to reject the giant directly,

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

Roro Anteng asked him to make her a sandy desert in between the mountains in one night. She hoped that the giant wouldn’t have the power to be able to fulfill her conditional request, moreover before daybreak.

But the giant magician started out to ac

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

omplish the unbelievable that very night. Alas, the giant began to work very swiftly. In witnessing this, Roro Anteng started to think about how to interrupt the giant’s work. At last she thought of an idea, so set out to make noises of all sorts that

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

eventually woke up the roosters. Finally the roosters began to crow, signaling the break of dawn.

On hearing the rooster’s calls, the giant was flabbergasted and became very sorrowful for having failed his task. Frustrated, he threw the coconut shell

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

batok) that he used to dig, which then fell to the ground beside Mount Bromo, forming what is now knows as Mount Batok. Conversely, the sandy plain was to form the Tengger caldera.

The story continues. Roro Anteng then met up with Joko Seger, a young

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

man who was a descendant of the great Majapahit Kingdom, who led a reclusive life on the desolate mountain range. Joko Seger and Roro Anteng soon fell in love and were married.; both live happily in peace and were blessed with many children. Their bloo

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

dline continued their legacy. With the turn of time they also gradually formed the tribal community of the Tengger (taken from the names ‘Roro Anteng’ and Joko Seger”). The Tengger tribe is now referred to as the aboriginals that occupy the Bromo area,

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

the place where their ancestors started their path of life from ancient times.

Surely this is the legend of the Bromo and Tenggerese origins that has been handed down from generation to generation… one among the many legends and myths that surround th

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

e Bromo mountain range.

It is not hard to understand these people’s way of life and beliefs. They live on the edge of a magnificent million-year-old caldera with four dormant and active volcanic peaks. Mount Bromo is one of the active and therefore he

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

humble character frequently reflected through the native people has become an inseparable part of their lives.

At those times when Bromo starts to grumble and cough it becomes a sign of a result of misconduct by the people. They will then proceed in i

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ntrospection to see what they had done wrong and make up for it. Moreover, every year a ceremony that involves offerings being brought to the top of Bromo as a taken of gratitude for the blessings of the past year takes place.

In order to ease the int

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

raction with nature, horses have likewise come into use as being the people’s best companions. These mighty beasts are not indigenous to Bromo, but have been introduced from other areas. The horse tradition is relatively new, after having opened doors

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

and having more contact with the outside world. But the adaptation of the Tenggerese as horsemen has fallen into place. Horses have in due courses and the Tenggerese have formed to become the dual icons of Bromo.

And the Tenggerese tribe that has for

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

enturies been a part of this natural legacy slowly but surely enters into the tourism industry by becoming native tour guides. They utilize their mighty and dutiful horses to carry visitors up the slopes of Bromo, or accompany sunrise hunters in their

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

4x4 Jeeps. All have become new ritual, and all have become new blessings for them.

Nature indeed continues to provide the blessing, and the Tengger tribe will continue this inherited harmonious relationship. The strong spiritual bonds will have no end

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

HTTP = HTML link (for blogs, profiles,phorums):
<a href="http://www.references.org.ua/article/324760/references-BROMO--Life-Legend-and-Natural-Grandeur.html">BROMO - Life, Legend and Natural Grandeur</a>

BB link (for phorums):
[url=http://www.references.org.ua/article/324760/references-BROMO--Life-Legend-and-Natural-Grandeur.html]BROMO - Life, Legend and Natural Grandeur[/url]

When we are designing our websites we should realize that people who visit them have no idea what our sites are about until we tell them.

You may not worry about your broadband setup as it is working well for you. But, its components like modem play a key role in its performance. ADSL or Cable? Know your modem here.

Love can build a bridge Between your heart an mine Love can build a bridge Don't you think it's time? Don't you think it's time?

Tags

Links

References - BROMO - Life, Legend and Natural Grandeur

Related Articles: