References - Travel and Leisure

I was outside my daughter's school the other day chatting with another parent when the subject of theme parks came up. This family was going to visit Alton Towers, to the obvious excitement of the

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

7-year son. Mum did not seem so keen. "It's costing a small fortune ", she groaned, because we have to stay in a hotel overnight. It's too far to drive there and back in a day". I asked why they

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

had chosen Alton Towers, since there are other theme parks that are much closer to us in the south of England. "Oh," came back the reply, "I thought Alton Towers was the only real theme park in En

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

land". It turned out that the trip was basically the idea of the 7-year-old boy, who under pressure not to be left out of the playground hierarchy had pestered them into agreeing to go.

This fami

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ly is likely to have a disappointing trip. They had basically decided to go to Alton Towers without doing any research on the alternatives or even considering whether Alton Towers was suitable for

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

their 7-year child. It is important that you research the U.K. theme parks before you visit to ensure that the theme park is suitable for the age range of any children that you are taking with you

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

. I suggest that you browse the theme park's web site with each child to see what appeals to them, and check out the height restrictions for the rides they get excited about. No point in getting t

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

e kids all hyper about a particular ride it they won't be allowed on. Height restrictions ARE strictly imposed and only when you reach the head of the queue will you find out if you are not allowe

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

d on the ride. Queueing a long time for a ride that you can't go on is a real waste of time and money.

Beware peer pressure from over-excited children and fathers. Make sure that the child is rea

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ly sure that they want to go and that you are not just going for yourself or Dad or because of some boastful child in the playground! Beware of childish bravado, which dissolves just as you are ab

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

out the board the ride. This has happened to me time and time again and is a great time waster.

If this is to be your first visit to a theme park try and go off peak. They can be very crowded at

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

peak times with long queues. It can all be a bit confusing and disorientating for both parents and children. Try and accept that you may not be able to do everything, particularly on your first vi

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

it, and this will lessen the tears. OK, so it's an expensive day out and you want your money's worth, but more importantly you want it to be enjoyable. By the way, many of the parks will give you

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

reduced price (or even free) entry for return trips to the park, so bare in mind that it may be relatively cheap to come back another day. Look out for the promotions on the web site, but often yo

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

will find that these reduced "return" visit offers are only advertised inside the park.

I guess what I am trying to say is that you must try and manage expectations. That way disappointment is l

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ess likely.

In general Legoland Windsor is aimed at children of 10 or under, with many Lego based rides which older children will find embarrassingly tame.

Chessington World of Adventures has be

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

n re-focused in recent years to appeal to the pre- and early teen market, i.e. 8-15, Some rides will appeal to older children, such as Vampire and Dragons Fury , but they may find many of the attr

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

actions too tame. There are sufficient rides to keep real youngsters happy too.

Thorpe Park is really suited to adventurous teenagers, as is Alton Park.

You should also not forget to consider ot

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

er fun parks that may be more local and suited to your child's age. These include :

Paultons Park in Hampshire

Flambards in Cornwall

American Adventure in Derbyshire

Camelot Theme Park in Lanc

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ashire

Crealy Park in Devon and Cornwall

Gullivers in Warrington, Matlock Bath and Milton Keynes

M & D Theme Park in Scotland

And of course many other amusement and theme parks of various size

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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