References - Home Improvement

Concrete is a composite material used commonly in building construction. It consists of a combination of a

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

n aggregate and a cement binder. The most common type of cement comprises Portland cement, mineral aggrega

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

tes and water. Concrete is the most widely used man-made material on earth.

Stained Concrete

Acid stain

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

is not a coloring agent or paint. It is basically, a coloring procedure that involves certain chemical rea

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ctions on cementitious material. Water, acid and inorganic salts react with the minerals present in the co

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

crete to form a solution that imparts it the color. Acid stains are made from hydrochloric acid, metallic

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ions and wetting agents. Acid stain provides a mottled, marble like look. It can create various beautiful

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

colors on the concrete such as earthy tones of red, green and reddish brown. Acid staining produces better

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

effects on old concrete. There are different kinds of acid stains available such as ChemTone. This stain

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

does not contain hydrochloric acid and is safer for transporting and handling. Acid staining is permanent,

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

it does not fade or chip.

Where and How to Do It?

Acid staining of concrete can be done in walks, entran

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ces, patios, driveways, living rooms and bathrooms. A smooth concrete surface is better for acid staining.

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

Application of acid stain requires few tools such as paintbrushes, sprayers and a saw with a diamond blad

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

e for scoring the surface. One gallon of stain with one gallon of water can color approximately 400 square

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

feet. A new concrete slab needs time for curing (at least three weeks after pouring the mixture). It also

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

has to be rinsed and scrubbed. Old concrete needs to be thoroughly cleaned as any dust, dirt or grease wil

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

l prevent the acid stain from penetrating properly. It is recommended to test the acid stain on a small ar

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ea first. Acid stains are transparent and any scratches or cuts on the concrete add to the charm. It is re

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

commended to apply the stain with non-metallic equipments. When the floor is dry, sealing is advised to en

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

hance the color and shield the concrete. The sealer can be applied with a phenolic core roller or sprayers

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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If we use technologies such as virtual reality, video conferencing and tele-commuting we can perhaps reduce pollution. By how much you ask? Well that is hard to say, what we need is some brilliant crack researchers to come along and figure out just how much we might save and how much pollution we might prevent by leveraging these high-tech methods.

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References - Concrete Acid Stain is Not a Coloring Agent or Paint

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