References - Home and Family

Genealogy is like a big Jigsaw Puzzle! If you don’t put the pieces together correctly, you’ll never see the full picture. So where do you start? This is the most common question asked. The answer is start with yourself and work backwards. Don’t get tempted to skip a few generati

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ons and run the risk of researching the wrong line. It’s better to be methodical and approach your research step by step. That way, you’ve less likely to research someone who isn’t your relative.

A simple but effective way to research your immediate generation is to construct a

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

chart of your family as far as you can go. Then interview and ask your relatives, especially parents and grandparents to fill in the gaps and add more information. This will kick start your research and probably provide about 100 years of history. Be sure to document this well.

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

n particular, identify each person with personal information such as the following:

• Name
• Important dates such as their birth, death and marriage (If applicable)
• Their occupation and interests
• Their relationship to other members of the family
• Their

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

irthplace address and other places of residence
• A Pedigree Chart allows you to list your pedigree such as your parents, grandparents, great grandparents and so on.
• A Family Work Group Sheet allows you to record the information of your entire family.

You need to p

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

int multiple copies of the above charts. Purchase a 3 ring binder to store the information. The charts will save you a heap of time and effort because it organizes your information in an orderly and simple format. You will soon notice what important information is missing and wh

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

t is incomplete. Don’t worry this is perfectly normal. This is where the fun begins as you begin to research more carefully. Organizing your information this way will help you avoid the pitfalls that most people face. It will help you establish the proper groundwork. Take small

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

teps; don’t go too far back yet. Be very sure about the information you have before you take the next step. Otherwise, you will end up researching the wrong ancestor. I recommend you document all your research so that you don’t go over old ground.

So, how do you fill in the gap

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

from your charts? I suggest you circle any missing information to highlight the gaps. As already mentioned you start with yourself and work backwards. You should bring together and document your own life first. Gather any records such as education, photographs, birth certificat

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

s, marriage, journals, and family bibles and so on. Then do the same thing for your parents, grandparents etc. All these documents could be a great source of information, providing important dates of events, places of residence, occupations and so on. It will bring your family h

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

story alive. If you’re visiting relative’s homes, be sensitive to their feelings and respectful. Ask permission to obtain copies of any documents, such as wills, Birth, Death and Marriage certificates. Official documents are a great source of information. They provide names, dat

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

es, places and information about other relatives. Involve them in your project. Explain you are personally interested in their personal history and tracing your roots.

Family documents, photographs and other documents can provide valuable information and point you to the right

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

irection in your research. Often photos and documents have dates and places written on the back of them. This can guide you to where to search for official records. Open your mind; often deceased ancestors have left many sources of information such as scrap books, old family bi

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

les, wills, Birth, death & marriage certificates, letters, postcards, journals, military records, Biographies and so much more.

As you speak to your family find out where relatives were married and buried. Churches and Cemeteries can be a good source of information. When visit

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ng the cemetery photograph the tomb stones of your relatives. They usually provide accurate dates and sometimes may reveal names of relatives you never knew existed. Often family members are buried in the same plot or nearby. Nearby unmarked graves may indicate children that die

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

in their infancy? Contact the cemetery administrators for more information.

Summary of sources to research:

• Birth, Death & Marriage Certificates
• Family Bibles
• Wills
• School Reports
• Photographs
• Scrap Books
• Letters
• Postcards

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

• Journals
• Military Records
• Biographies
• Churches
• Cemeteries

CONCLUSION

Be patient, persistent and don’t completely rely on people’s memories. They can be inaccurate. The most reliable information comes from primary official sources, but you should

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ave an open mind. You never know where you could pick up a lead. Keep all information no matter how insignificant it may seem. Often a piece of information that doesn’t initially fit makes perfect sense later when new pieces of information become available. Then the jigsaw puzzl

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

begins to reveal its full picture. Finally, be organized and keep detailed accurate records. Your next step will be to utilize community, state, national and worldwide resources. If you need help and want to save a lot of time and money check out my Genealogy Starter E-Book. It

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

contains valuable information on how to start your Family History, outlines a 5 step quick guide, reviews the best internet sites, shows you where to get free Computer Genealogy Software and outlines numerous resources worldwide to do research. http://www.genealogy4beginners.co

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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