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References - There's a Snake In The Yard! What to Do (and not do) When You See a Snake
First, don't kill nonvenomous snakes. Any given area can only support a fixed number of snakes. If you kill the nonvenomous snakes that leaves a food supply that could support a population of ven
According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
omous snakes.
Remember to stay a safe distance from the snake. Snakes usually strike about 1/2 their body length, but they can strike farther. You also don't want to trip and fall on the snake.
Remember to stay a safe distance from the snake. Snakes usually strike about 1/2 their body length, but they can strike farther. You also don't want to trip and fall on the snake.
; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.
Examples of combination products may in
Examples of combination products may in
80% of bites occur when someone tries to catch or kill a snake. The safest thing you can do if you see a snake is to leave it alone. (It's probably protected by law anyway.)
85% of bites in the
85% of bites in the
lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.
nited States occur on the hand and forearm. 50% involve a victim under the age of 20. 70% of bites in the United States involve alcohol consumption.
If you have a snake in your yard, either call
If you have a snake in your yard, either call
here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
someone trained in their removal or stand at a safe distance and spray it with a garden hose. Snakes hate that and will leave quickly.
Step on logs rather than over them. Snakes coil beside logs
Step on logs rather than over them. Snakes coil beside logs
d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.
Combination pro
Combination pro
in the "Reinert Posture" and might mistake your leg for a predator or prey.
Watch where you put your hands and feet. Do not reach under boards with your fingers.
Snakes can be handled safely w
Watch where you put your hands and feet. Do not reach under boards with your fingers.
Snakes can be handled safely w
ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
th proper tools and training, but do NOT risk trying to handle venomous snakes if you have not been professionally trained. There are things that no website can teach you about how to handle veno
easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
ous snakes safely.
You can minimize the appeal of your yard to a snake by 1. cutting the grass, 2. picking up debris, and 3. Controlling rodents. If there is no food or shelter the snake will so
You can minimize the appeal of your yard to a snake by 1. cutting the grass, 2. picking up debris, and 3. Controlling rodents. If there is no food or shelter the snake will so
nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
n leave for better hunting grounds.
The safest thing to do if you see a snake is to LEAVE IT ALONE. Most bites occur when someone is attempting to capture or kill a snake.
If you are bitten by
The safest thing to do if you see a snake is to LEAVE IT ALONE. Most bites occur when someone is attempting to capture or kill a snake.
If you are bitten by
and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
a snake, seek immediate medical care from a licensed and experienced physician. According to the Centers for Disease Control, the first aid for snakebite consists of:
"Do remain calm - Remember
"Do remain calm - Remember
ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
hat there is an excellent chance for survival, and in most cases there is plenty of time.
Do suck and squeeze - as much venom as possible directly from the wound. Venom is protein and can be tak
Do suck and squeeze - as much venom as possible directly from the wound. Venom is protein and can be tak
ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.
Following aspects would a
Following aspects would a
n orally with no ill effects.
Do remove jewelry - Swelling can progress rapidly, so rings, watches and bracelets can be a real problem.
Do mark the time - The progress of symptoms (swelling) is
Do remove jewelry - Swelling can progress rapidly, so rings, watches and bracelets can be a real problem.
Do mark the time - The progress of symptoms (swelling) is
dd to the challenges in developing combination products:
Which markets to tap where the combination products can do fairly well?
Which combination prod
Which markets to tap where the combination products can do fairly well?
Which combination prod
the most obvious indicator of the amount of envenomation.
Do keep the stricken limb below the heart.
Do get to a hospital as quickly as possible - Anti-venom serum is the only sure cure for env
Do keep the stricken limb below the heart.
Do get to a hospital as quickly as possible - Anti-venom serum is the only sure cure for env
cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
enomation, and because some people are allergic to horse serum it should only be given in a fully equipped medical facility.
In case of a Coral bite, do pull the snake off immediately - Corals'
In case of a Coral bite, do pull the snake off immediately - Corals'
tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
angs are relatively small, and they have to work at getting venom into the wound. Therefore, the faster the snake is removed the less venom is injected.
Do attempt to identify the offending snak
Do attempt to identify the offending snak
t?
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
- Positive identification in the form of a dead snake is helpful, if convenient, but no time or safety should be wasted since the symptoms will give medical personnel an accurate diagnosis.
Do
Do
ping new procedures for reviewing their safety, efficacy and quality.
Professional from academic institutions, pharmaceutical industries, health care indust
Professional from academic institutions, pharmaceutical industries, health care indust
et a tetanus shot.
Don't cut the wound - This almost always causes more damage than it's worth.
Don't use a tourniquet - This isolates the venom in a small area and causes the digestive enzymes
Don't cut the wound - This almost always causes more damage than it's worth.
Don't use a tourniquet - This isolates the venom in a small area and causes the digestive enzymes
y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
in the venom to concentrate the damage.
Don't use alcohol orally - it speeds the heart and blood flow and reduces the body's counter-acting ability.
Don't use ice - Freezing the stricken limb
Don't use alcohol orally - it speeds the heart and blood flow and reduces the body's counter-acting ability.
Don't use ice - Freezing the stricken limb
.
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
as been found to be a major factor leading to amputation."
Remember, snakes have their place in the ecosystem and were around long before we arrived. We are the visitors in their garden. Snakes
Remember, snakes have their place in the ecosystem and were around long before we arrived. We are the visitors in their garden. Snakes
elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.
Companies that provide selfless information through particip
Companies that provide selfless information through particip
re quite capable of defending themselves, but are reluctant to do so. If you follow a few common sense rules you can minimize an already very small risk of snakebite during your outdoor adventure
tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products
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