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Wouldn't you like to be able to create your own artistic silk scarf? Well, you can. With a few tools from the arts & crafts supply store and a little imagination, you can have a beautiful silk scarf in

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

a few hours!

Begin by using whatever supplies you might have at home already. Paint brushes, plastic pans and buckets, styrofoam cups and plates, sponges, rubber gloves, paper towels, white vinegar and

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

alt crystals.

Now go to the arts & crafts store and find three acrylic paints that you like, plus one or two metallic ones such as gold and silver. Then go to the fabric store and find ready silk scarve

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

s or silk fabric suitable for scarves, such as an 8-10 mm habotai silk.

Prepare a well-ventilated area at home with a small table covered with plastic. Take the silk fabric or scarf and soak it in the h

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

lf white vinegar, half water mixture in a pan or bucket. While the silk is soaking, take out your paints and styrofoam cups, mix about a tablespoon of acrylic paint with a tablespoon of water, stir with

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

brush until the mixture is even and no pigments are floating around. Do this with each color you've selected, even the metallics.

Take the soaked silk fabric, wring it out under running water quickly,

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

and take it to the table where you're working. At this point you can take paper towels and spread them out to cover the table or the area where you will be placing the silk scarf. Lay the fabric piece o

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

top of the paper towels.

Now take one of your acrylic colors and make broad brush strokes in any pattern on the scarf. Take another color and do the same, overlapping here and there with the first colo

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

. Follow this with the third color by dripping the paint from the brush all over the scarf. Notice how the various colors will run into each other and make interesting abstract patterns, sometimes takin

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

g the texture from the underlying paper towels.

Have another silk scarf soaking in the vinegar-water mixture while you're painting the first piece. While it is drying slightly to the point the colors ar

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

n't running any longer, think about your next color combination for the scarf soaking in the bucket. You might want to add some metallic gold or silver this time with a finer brush. You might also sprin

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

le some salt crystals onto the fabric at this point and see what happens.

As soon as the first scarf is no longer wet and you can lift it off the papertowels, place it gently onto a styrofoam plate and p

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ut it into the microwave oven for 1-1.5 min. on medium. This will heatset the paints nicely and dry the silk scarf more. Take it out and hang it to air dry outside if you can or in the laundry room near

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

an open window. Sometimes the vinegar odor lingers a while but most of the time it's gone by the time the scarf is dry.

Keep this procedure going for as many silk scarves as you want to make. Change ou

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

the paper towels in between, but save them for another painting session. The paper towels will dry in pretty color patterns and can be used again. The brushes can be used again, just clean them in soap

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

and water. The cups and plates can be reused as well, just run water over them and make sure any paint residue is gone. I use thin rubber gloves to protect my hands but you can do this if you're neat a

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

d careful about rinsing your hands in between things.

Try scrunching the fabric, try twisting it into a long sausage, try folding it into pleats and see what happens when you drip the paints over these.

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

Have some paints in applicator tip bottles and spray bottles if you like for added effects. Don't be afraid to experiment with color combinations and techniques, that's the whole idea here. Have fun!

A

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

fter the silk scarves have dried, I then iron them with a medium iron and I sometimes sprinkle water on them if they're really wrinkled from the process. Then sign your creations with a permanent fabric

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

nk pen and give them away as gifts to friends and family!

Now go to my website at www.katrinasjoberg.com and see what I've done with silk scarves

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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References - How To Make Your Own Handpainted Silk Scarf

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