References - Home and Family

Thymus is a genus of over 400 species of aromatic hardy and non-hardy perennials with very smal

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

l, fragrant leaves and twiggy stems. Thymes are native to Mediterranean Europe, as far as the B

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ritish Isles. These wonderful herbs have long been cultivated for their neat and orderly appear

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ance in the container, border, rock garden and dry walls. The creeping varieties are excellent

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

as ground covers or fill in between pavers. Thymes grow wild on the hillsides in Greece and we

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ll-known in the ancient world. Sumerians used it as a medicinal herb, and Egyptians used it as

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

an ingredient in mummification. Thyme was used by the Greeks as a temple incense; the word thym

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

e comes from a Greek word meaning "to fumigate". The Greeks and Romans used hyme for its healin

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

g properties. It was thought to be an aphrodisiac and was enthusiastically strewn around banque

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

t halls in the Middle Ages! Thyme was considered to be a symbol of courage, knights rode into

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

attle with sprigs of thyme embroidered into their scarves. Shakespeare speaks of thyme in A Mid

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

summer Night's Dream:

"I know a bank where the wild thyme grows", says King Overon, king of th

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

e fairies.

Thyme

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

> is an easy herb to grow; all thymes need full sun and dry, light, well-draining soil. If grow

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

n in too rich soil, the plant tends to grow excessively and makes the plant susceptible to dise

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ase and winterkill. Keep thymes well cut back in the growing season so that they do not get too

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

woody. Once the plant develops an open center, either divide the plant or replace. If growing

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

in a humid area, watch for fungus. They do not like "wet feet"! Thyme does grow well indoors o

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

n a sunny windowsill.

Thyme is a major culinary herb and has a wonderful aroma. You can use th

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

yme in a multitude of dishes, either fresh or dried. Harvest the leafy tops and flower clusters

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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References - Growing Thyme

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