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Father's Day has today become a global symbol of expressing love and respect to one

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

's father. Sons and daughters all over the world make it a point to take some time

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

off and meet their father on this day.

Father's Day has religious as well as socia

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

l origins. In the Roman Catholic tradition, it is celebrated on Saint Joseph's Day.

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

Saint Joseph's Day is marked to commemorate Saint Joseph, husband of Mary and foste

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

r-father of Jesus.

In the social context, Father's Day as a national celebration c

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

an be credited to one woman, who is known to be the founder of Father's Day celebra

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ions in the USA. Mrs. Sonora Smart Dodd, a resident of Spokane, Washington, was one

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

of six siblings who were taken care of by a single father.

Her father, William Ja

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ckson Smart, was a Civil War veteran who raised his children after their mother's d

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ath. It is said that while she was inspired by Anna Jarvis's work to establish Moth

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

er's Day, she actually hit upon the idea while listening to a Mother's Day sermon.

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

Sonora's father was born in June; therefore, they tried to celebrate Father's Day

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

in June. The first Father's Day was celebrated on June 19, 1910, in Spokane, Washin

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ton. Various people like William Jennings Bryan supported this celebration on an un

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

official basis. Later, Woodrow Wilson was personally honored by his family on Fathe

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

r's Day in 1916. Calvin Coolidge recommended it as a national holiday eight years l

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ter. The National Father's Day committee was formed in New York City in 1926.

In 1

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

966, Lyndon Johnson made it a holiday to be celebrated on the third of June, while

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

the holiday was officially recognized under the presidency of Richard Nixon in 1972

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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References - Fathers Day History

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