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References - Goldfish Disease Prevention And Treatment
Many goldfish are imported in very cold water, in crowded conditions, making them very susceptible to disease (espec
According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
ially ich). Although goldfish are not very particular about water conditions, they still do better at a ph of 7.2 to
; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.
Examples of combination products may in
Examples of combination products may in
7.8 and a high mineral content (especially calcium and magnesium- KH of 80 ppm or more).
Goldfish also are basical
Goldfish also are basical
lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.
y “grazing fish” and need to be fed frequent small amounts of fish food that are not made from animal based products
here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
Goldfish do well on foods high in vegetable based proteins (such as spirulina), they need a high fat content and V
d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.
Combination pro
Combination pro
tamins C & E, and carotenoid for color enhancement.
Canister filters are great for goldfish, due to there high effi
Canister filters are great for goldfish, due to there high effi
ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
ciency and great bio load and mechanical filtration abilities (although make sure to clean them regularly, or they
easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
ecome nitrate factories). Unfortunately they are generally expensive. A combination of “hang on back” filters (such
nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
s ReSun and Aqua Clear) and sponge filters are an excellent combination for less money.
Regular water changes are a
Regular water changes are a
and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
must. A small 20% change once per week is best (sometimes larger less frequent changes can be performed as per one’s
ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
busy schedule). Using a gravel vacuum is the best and easiest way to change water (a new device called an ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.
Following aspects would a
Following aspects would a
ttp://americanaquariumproducts.com/CleaningMachine.html" target="_blank">"Aquarium Cleaning Machine" is awesome
dd to the challenges in developing combination products:
Which markets to tap where the combination products can do fairly well?
Which combination prod
Which markets to tap where the combination products can do fairly well?
Which combination prod
or larger tanks). Make sure the water is of similar ph and temperature and has no chlorine or choramine when you add
cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
it to your aquarium.
Remember, goldfish are dirty animals, can grow up to 12” (or more), so house them in an approp
Remember, goldfish are dirty animals, can grow up to 12” (or more), so house them in an approp
tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
iate aquarium for good health and long life. Even if you start out with a ten gallon aquarium, I recommend moving up
t?
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
to a 45-60 gallon aquarium as soon as possible.
Add or subtract many of these points, and your goldfish may have pr
Add or subtract many of these points, and your goldfish may have pr
ping new procedures for reviewing their safety, efficacy and quality.
Professional from academic institutions, pharmaceutical industries, health care indust
Professional from academic institutions, pharmaceutical industries, health care indust
oblems. I recommend ”Wonder
y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
Shells” (For ph and KH control) or "Medicated Wonder Shells" for prevention and/ or treatment of goldfish diseas
.
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
(ich/ fungus), and water conditions. Of coarse good maintenance, proper feeding, proper filtration, are not replace
elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.
Companies that provide selfless information through particip
Companies that provide selfless information through particip
by this product. I have used this product on my aquarium maintenance route (27 years experience) with GREAT results
tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products
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