References - Food and Drink

What better on a cold winter’s night, than to come home to a supper of crisp-skinned baked potato, piping ho

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

t, a knob of butter soaking into the fluffy centre. Perfect for days when you get home in good time but have

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

a million things to do and cooking supper is last on the list. All you have to do is get the oven hot (200C

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

), fling them in, (with a cross scored on the top, so they don’t burst and coat your oven with an irremovabl

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

patina of flaked potato) and leave them there for at least an hour, better an hour and a half. You can get

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

on with everything else, secure in the knowledge that supper is cooking without you and then put together a

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

few fillings at the last minute.

One of my favourite toppings is tuna. Just open the tin, drain, season wi

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

th salt and pepper and some lemon juice (feel free to add mayonnaise if you like it but we don’t). Other has

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

le-free accompaniments are baked beans, grated cheese, left-over juices from last night’s stew. Any of these

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

makes a tasty, nutritious meal with no fuss and best of all, one that most kids will eat...an enormous plus

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

point for mothers everywhere.

A microwave hastens the process but leaves you with thin skinned potatoes th

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

at might do as an accompaniment to something else but lose the crisp appeal of the true oven baked article.

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

f you are in a hurry, cook pasta instead and save your jacket or baked potatoes for a day when you remember

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

to switch the oven on in time.

A variation to try with smaller potatoes: after washing, drying and scoring

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

the potatoes, rub the skins with a little butter, then season with salt and pepper before baking to give you

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

extra crispy, tasty skins that everyone will eat.

Another thing to try if you want to get fancy: once the

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

otatoes are cooked, halve them, scoop out the insides, mix with a beaten egg, grated cheese, salt and pepper

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

, heap the mixture back into the skins and return to the oven for another 15 minutes until the tops are gold

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

en brown. A meal in itself!

Cheap, filling, nutritious with the right toppings and needing the minimum inve

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

stment of labour, the baked potato is every busy mother’s ideal supper!

Copyright 2006 Kit Heathcock

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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References - A Hymn To Baked Potatoes

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