References - Food and Drink

Cooking with clay has grown in popularity, and it’s no wonder why. Using clay cookware produces fabulous meals which are moist a

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

nd tender, and are both flavorful and nutritious. Before cooking, unglazed clay pots are soaked in water. A moist clay pot will

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

roast and steam food at the same time. This cooking process retains the food's natural flavor and nutrients. Little fat or addit

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ional liquid needs to be added to the food. Clay pot cooking makes low-fat, nutrient-rich foods that taste good, too.

Cooking i

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

unglazed clay is nothing new. The earliest cooking pots created by people were made of clay. Clay pots are still the preferred

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

cooking vessels in many parts of the world. Clay distributes the heat evenly and retains heat well. Unglazed clay cooking pots c

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

an be used in the oven or microwave. They should not be used on the stove top without placing a heat diffuser between the burner

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

and the clay. (Follow the manufacturer's instructions for stove top cooking.)

When you get a new clay cooker, you will need to

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

soak and clean it before use. Soak the pot and the lid in cool water for 30 minutes. Scrub both pieces with a stiff brush to rem

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ove any clay dust. Each time you use your clay pot, you will need to soak it in water for 10 to 15 minutes.

Clay pots can crack

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

if they are exposed to sudden changes in temperature. Some manufacturers recommend starting the cooking process in a cool oven.

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

In other words, don't preheat. When you remove a clay pot from the oven, place it on a hot pad or towel, not a metal trivet. The

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

cold metal can crack the bottom of the clay pot.

When making a traditional recipe in an unglazed clay pot, raise the temperatu

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

re of the oven between 50 and 100 degrees. Don't start the timer until you've given the pot time to warm up.

When you're done c

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

oking, allow your clay pot to cool completely before you clean it. Never use any type of soap or cleanser on the clay. The porou

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

s surface will absorb the cleaner and give your food a soapy taste. To clean, scrub the clay cooker with warm water and a stiff

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

brush. Use salt or baking soda to clean the surface. To loosen baked-on food, soak the pan in water that has baking soda added.

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ever place your clay cooking pot in the dishwasher.

Be sure to dry your pot thoroughly before storing. It's possible for unglaz

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ed clay to become moldy. If possible, store the clay pot with the lid off or invert the lid and place a towel between the two pi

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

eces. If you take care of your clay cookware, it will stay in tip top shape, and provide you with many years of cooking pleasure

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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References - Using and Caring For Clay Cookware

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