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The Chinese love of gambling is well known; yet what is less well-known is that there are few casinos operating anywhere in

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

China, including Hong Kong. The government of China has a somewhat negative attitude towards casinos, and gambling more ge

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

nerally, and discourages it wherever possible. Therefore, Hong Kong casinos get around this official prohibition in a numbe

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

r of ingenious ways.

Although there are no officially sanctioned Hong Kong casinos, gambling in Hong Kong is actually rema

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

rkably easy. The most obvious method of gambling is to go to nearby Macao; the former Portuguese enclave is only a short hy

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

drofoil ride away, less than an hour from Hong Kong. In Macao, gambling is not only permitted, but it is the prime attracti

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

on for tourists visiting from Hong Kong and elsewhere. There is an official age limit of 21, and passports are required for

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

the journey, but otherwise, Hong Kong gamblers will find the trip to Macao more than worthwhile - always provided they win

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

, of course!

There are a large number of casinos in Macao that cater to every type of gambler, whether they are playing fo

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

r high stakes or low, and however dressed. China is well aware that many people come to Macao for the gambling, including t

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ousands of tourists from Hong Kong, and so China is happy to permit the sport to continue. Indeed, Chinese people are well

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

known for their addiction to gambling of all sorts, and consequently, the casinos are almost always full.

Another aspect o

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

f the Hong Kong casino scene is offshore gambling, which allows Hong Kong tourists to gamble on board specially appointed c

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ruise ships and boats in international waters off the coast of Hong Kong, thus getting around the rules that prevent the ex

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

istence of Hong Kong casinos. Publicity for these cruises rarely features gambling very prominently, but nonetheless, there

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

are many operators offering voyages that include the opportunity to gamble at leisure in an onboard casino. Of course, the

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

se journeys also offer the chance to enjoy spectacular views of Hong Kong harbor when entering and leaving the former colon

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

y. As a result, these voyages are extremely well subscribed to and growing in popularity every year. They are an enjoyable

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

addition to the usual itinerary of the visitor to Hong Kong, and accordingly, there are plenty of opportunities for tourist

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

s visiting Hong Kong to enjoy the excitement and glamor of visiting a casino and indulging in this most Chinese of pastimes

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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